Born July 22, 1964, in Bogotá, Colombia, Leguizamo was four when his family immigrated to the United States. He was raised in Queens, New York, attended New York University and studied under legendary acting coach Lee Strasberg for only one day before Strasberg passed away. The extroverted Leguizamo started working the comedy club circuit in New York and first appeared in front of the cameras in an episode of "Miami Vice" (1984). His first film appearance was a small part in “Mixed Blood” (1984), and he had minor roles in “Casualties of War” (1989) and “Die Hard 2” (1990) before playing a liquor store thief who shoots Harrison Ford in “Regarding Henry” (1991).

His career really started to soar after his first-rate performance in the independent film “Hangin' with the Homeboys” (1991) as a nervous young teenager from the Bronx out for a night in brightly lit Manhattan with his buddies, facing the career choice of staying in a supermarket or heading off to college and finding out that the girl he loves from afar isn't quite what he thought she was.

The year 1991 was also memorable for other reasons, as he hit the stage with his show “Mambo Mouth” (1991), in which he portrayed seven different Latino characters. The witty and incisive show was a smash hit and won the Obie and Outer Circle Critics Award, and later was filmed for HBO, where it picked up a CableACE Award.

In 1995 he created and starred in the short-lived TV series "House of Buggin'" (1995), an all-Latino-cast comedy variety show featuring hilarious sketches and comedic routines. The show scored two Emmy nominations and received positive reviews from critics, but it was canceled after only one season. The gifted Leguizamo was still keeping busy in films, with key appearances in “Super Mario Bros.” (1993), “Romeo + Juliet” (1996) and “Spawn” (1997). In 1998 he made his Broadway debut in “Freak” (1998), a "demi-semi-quasi-pseudo-autobiographical" one-man show, which was filmed for HBO by Spike Lee.

Utilizing his distinctive vocal talents, he next voiced a pesky rat in “Doctor Dolittle” (1998) before appearing in the dynamic Spike Lee-directed “Summer of Sam” (1999) as a guilt-ridden womanizer, as the Genie of The Lamp in the exciting “Arabian Nights” (2000) and as Henri de Toulouse Lautrec in the visually spectacular “Moulin Rouge!” (2001). He also voiced Sid in the animated “Ice Age” (2002), co-starred alongside Arnold Schwarzenegger in “Collateral Damage” (2002) and directed and starred in the boxing film “Undefeated” (2003). Afterward, Leguizamo starred in the remake of the John Carpenter hit “Assault on Precinct 13” (2005) and George A. Romero's long-awaited fourth "Dead" film, “Land of the Dead” (2005). There can be no doubt that the remarkably talented Leguizamo has been a breakthrough performer for the Latino community in mainstream Hollywood, in much the same way that Sidney Poitier crashed through celluloid barriers for African-Americans in the early 1960s. Among his many strengths is his ability to not take his ethnic background too seriously but also to take pride in his Latino heritage. He has opened many doors for his countrymen. A masterly and accomplished performer, movie audiences await Leguizamo's next exciting performance.